If you take liquid tadalafil, shake the bottle well for 30 seconds before use. Use an accurate measuring device to measure your dose. A household spoon is not an accurate measuring device and may cause you to take the wrong dose.
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The most common side effects of tadalafil are listed below. The side effects may vary depending upon the condition being treated. Tell your healthcare provider if you have any of these side effects that bother you. Pain in your muscles, back, arms, or legs There may be other side effects of tadalafil that are not listed here. Contact your healthcare provider if you think you are having a side effect of a medicine.
What should I do if I miss a dose of tadalafil?
In the U.S., you can report side effects to the FDA at or by calling 800-FDA-1088. In Canada, you can report side effects to Health Canada at or by calling 866-234-2345. While less common, the most serious side effects of tadalafil are described below, along with what to do if they happen. Tadalafil may cause allergic reactions, which can be serious. Stop taking tadalafil and get help right away if you have any of the following symptoms of a serious allergic reaction. Ask your pharmacist to recommend an appropriate measuring device.
| Product | Dosage | Quantity + Bonus | Price | |
|---|---|---|---|---|
| Cialis Original | 20mg | 76 + 4 Pills | 319.19€ 303.99€ | |
| Cialis Black | 80mg | 10 Pills | 43.27€ 41.21€ | |
| Cialis Generic | 20mg | 120 + 8 Pills | 188.15€ 179.19€ | |
| Cialis Generic | 2.5mg | 10 Pills | 28.51€ 27.15€ | |
| Cialis Black | 80mg | 20 Pills | 71.83€ 68.41€ | |
| Cialis Generic | 10mg | 120 + 6 Pills | 178.49€ 169.99€ | |
| Cialis Generic | 5mg | 20 Pills | 41.99€ 39.99€ | |
| Cialis Professional | 40mg | 120 + 4 Pills | 436.68€ 415.89€ | |
| Cialis Generic | 5mg | 180 + 10 Pills | 159.65€ 152.05€ | |
| Cialis Professional | 40mg | 30 Pills | 148.94€ 141.85€ | |
| Cialis Generic | 20mg | 20 Pills | 54.72€ 52.11€ | |
| Cialis Generic | 10mg | 30 + 4 Pills | 63.32€ 60.30€ | |
| Cialis Generic | 5mg | 30 + 4 Pills | 53.56€ 51.01€ | |
| Cialis Black | 80mg | 90 + 6 Pills | 207.88€ 197.98€ | |
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Tell your healthcare provider about all of your health conditions and any prescription or over-the-counter (OTC) medicines, vitamins/minerals, herbal products, and other supplements you are using. This will help them determine if tadalafil is right for you. In particular, make sure that you discuss any of the following. Tell your healthcare provider if you have any of the following.
| Study Type | Population | Success Rate (%) | Notes |
|---|---|---|---|
| Clinical Trials | Men with ED | 70-80 | Effective in most cases |
| Real-world Data | Men taking Cialis regularly | 65-85 | Consistency improves results |
| Comparative Studies | Cialis vs. other PDE5 inhibitors | Similar efficacy | Slight differences in onset/duration |
Heart problems, such as heart rhythm problems, chest pain, or heart failure Heart attack, stroke, or heart surgery within the past six months High blood pressure that is still too high despite taking medicines for it Peyronie's disease, or a penis with an abnormal curve or shape An erection lasting longer than four hours A blood disorder, such as sickle cell anemia, multiple myeloma, or leukemia An inherited eye disease called retinitis pigmentosa Vision loss, or a problem with the nerve between your eyes and brain (optic nerve) Health conditions or factors that raise the risk of optic nerve problems, such as diabetes, high cholesterol, smoking, being older than 50, or having a “crowded disc,” which is something an eye doctor may see in an eye exam Pulmonary veno-occlusive disease, a condition where blood vessels in the lungs are blocked It is not known if or how tadalafil could affect pregnancy or harm an unborn baby. Tell your healthcare provider if you are or plan to become pregnant.
- Patients should avoid excessive alcohol consumption when using Cialis.
- Using Cialis with other ED medications can increase the risk of adverse effects.
- Always check with your healthcare provider before combining medications.
Your healthcare provider will advise you if you should take tadalafil while you are pregnant or trying to get pregnant.
What is Tadalafil (Cialis)?
Swelling of the face, lips, mouth, tongue, or throat Itching, skin rash, or pale red bumps on the skin called hives Tadalafil may cause an unwanted erection that is persistent, painful, and that may occur without sexual arousal. Permanent damage to the penis may occur if priapism is not treated quickly. Stop taking tadalafil and get emergency help right away if you have any of the following symptoms of priapism. Erection lasting for more than 4 hours Erection that is unrelated to price cialis super active sexual stimulation If you feel faint or dizzy, lie down. Tell your healthcare provider right away if you have any of the following symptoms of low blood pressure.
What are the serious side effects of tadalafil?
Tadalafil can cause mild, temporary vision changes such as seeing a blue tint, abnormal colors, blurry vision, or sensitivity to light. Though rare, some people have reported permanent vision loss. Stop taking tadalafil and get help right away if you have sudden vision loss in one or both eyes. Tadalafil may cause a sudden decrease or loss of hearing. Stop taking tadalafil and tell your healthcare provider right away if you experience hearing loss or have any of the following symptoms. It is not known if tadalafil passes into breast milk. Tell your healthcare provider if cialis help with premature ejaculation you are breastfeeding or plan to breastfeed. Your healthcare provider may recommend limiting or avoiding grapefruit while taking tadalafil. Grapefruit or grapefruit juice can raise tadalafil levels in your body, which can increase the risk of side effects.
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If you feel chest pain, dizziness, or nausea during sex, stop and contact your healthcare provider right away. Tadalafil does not protect against sexually transmitted infections, including HIV. Tadalafil belongs to a group of medicines, known as phosphodiesterase-5 (PDE-5) inhibitors, which are used to treat erectile dysfunction or pulmonary arterial hypertension. You should not take more than one PDE-5 inhibitor medicine. Medicines in this group include avanafil (Stendra), sildenafil (Viagra, Revatio, and others), tadalafil (Cialis and others), and vardenafil (Levitra, Staxyn). It is unknown if drinking alcohol will affect tadalafil. The risk of low blood pressure and dizziness may be increased if you drink alcohol while taking tadalafil. It is best to limit the amount of alcohol you drink while taking tadalafil.
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People who are allergic to any of the following should not take tadalafil. Any of the ingredients in the specific product dispensed Your pharmacist can tell you all of the ingredients in the specific tadalafil products they stock. Tadalafil should not be taken while you are using certain other medicines. Before taking tadalafil, tell your healthcare provider about any prescription or over-the-counter (OTC) medicines, vitamins/minerals, herbal products, and other supplements you are using. See the Interactions section for more details.
What could be improved
Do not take tadalafil unless it has been prescribed to you by a healthcare provider. Do not share tadalafil with other people, even if they have the same condition as you. Keep tadalafil out of the reach of children. Sexual activity can put extra strain on your heart, which may be unsafe for people with certain health problems, such as a recent heart attack. Talk to your healthcare provider to see if your heart is strong enough for sex. Always tell your healthcare provider about any prescription or over-the-counter (OTC) medicines, vitamins/minerals, herbal products, and other supplements you are using.
- Do not use Cialis if you are allergic to tadalafil or any ingredients in the medication.
- Always follow your healthcare provider's instructions precisely.
- Regular follow-ups may be necessary to monitor your response to the medication.
In particular, make sure that you discuss if you are using any of the following before taking tadalafil.
- Cialis is not suitable for individuals with certain medical conditions like severe liver or kidney disease.
- It is important to disclose your complete medical history to your healthcare provider.
- Cialis should be used cautiously if you have a history of heart problems or stroke.
A nitrate, such as nitroglycerin (Nitro-Dur, Nitrostat, and others) or isosorbide, which is a medicine used for chest pain caused by a type of heart disease, or a street drug, such as amyl nitrite (“poppers”) A guanylate cyclase stimulator, such as riociguat (Adempas), which is a medicine used for high blood pressure in the lungs (pulmonary arterial hypertension), or vericiguat (Verquvo), which is a medicine used for a type of heart failure An alpha-blocker, such as alfuzosin (Uroxatral), doxazosin (Cardura), dutasteride, prazosin (Minipress), silodosin (Rapaflo), tamsulosin (Flomax), or terazosin (Hytrin), which is a medicine that may be used for high blood pressure and/or difficulty peeing due to an enlarged prostate A blood pressure medicine, such as amlodipine (Norvasc) or enalapril (Vasotec) Bosentan (Tracleer), which is a medicine used for pulmonary arterial hypertension A protease inhibitor, such as ritonavir (Norvir), which is a medicine commonly used to treat HIV Rifampin (Rifadin), which is a medicine commonly used to treat an infection called tuberculosis A medicine used for fungal infections, such as ketoconazole or itraconazole (Sporanox, Tolsura) Erythromycin (Ery-Tab and others) or clarithromycin (Biaxin), which is a medicine used for bacterial infections Any other medicine used for erectile dysfunction or pulmonary arterial hypertension Some other medicines may alter the blood levels of tadalafil. Tell your healthcare provider about all medicines that you take or have recently taken. This may not be a complete list of medicines that can interact with tadalafil.
| Medication Type | Specific Drugs | Potential Effect |
|---|---|---|
| Nitrates | Nitroglycerin, Isosorbide dinitrate | Severe hypotension risk |
| Alpha-blockers | Tamsulosin, Doxazosin | Enhanced blood pressure effects |
| CYP3A4 inhibitors | Ritonavir, Ketoconazole | Increased Cialis levels, risk of side effects |
| Other PDE5 inhibitors | Sildenafil, Vardenafil | Increased risk of adverse effects |
If you or someone else has used too much tadalafil, get medical help right away, call 911, or contact a Poison Control center at 800-222-1222.
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I am feeling better now after visiting clinic New York urology specialists. by George & Sally R on Jan 07, 2013 Dear Dr. Alex: We want to thank you for the excellent care you provided for George during his emergency operation and the follow up treatment. Your quiet, confident manner was reassuring to us during a very scary time for us. by Joyce T on Feb 16, 2012 Dr.
How should I store tadalafil?
Alex Shteynshlyuger and Staff – Thank you so much for taking care of my husband Bob. Dr. Alex: I thank God everyday for you. Tadalafil is a medicine that is commonly used for the following conditions. Erectile dysfunction, a condition where you have trouble getting or keeping an erection Pulmonary arterial hypertension, a condition where you have high blood pressure in the blood vessels that carry blood from your heart to your lungs Benign prostatic hyperplasia (BPH), a condition where the prostate gland has become enlarged Tadalafil may also be used for other conditions as determined by your healthcare provider. If you miss a dose, take it as soon as you remember.
| Parameter | Value | Details |
|---|---|---|
| Half-life | ~17.5 hours | Time to eliminate half the drug |
| Absorption | Rapid, peaks in 2 hours | Taken with or without food |
| Metabolism | Liver (CYP3A4 enzyme) | May interact with other drugs metabolized here |
| Excretion | Feces (~61%), Urine (~36%) | Primary pathways of elimination |
If it is almost time for your next dose, skip the missed dose and only take the next dose.
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Tadalafil works by blocking the activity of an enzyme called phosphodiesterase 5 (PDE5). This enzyme usually stops some types of muscles from relaxing, including the muscles lining some types of blood vessels. By blocking PDE5, the muscles will relax and blood flow increases. For erectile dysfunction, it increases blood flow to the penis when aroused. This makes it easier to get and keep an erection.
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For pulmonary arterial hypertension, tadalafil relaxes the blood vessels in the lungs. This lowers blood pressure and reduces strain on the heart. For benign prostatic hyperplasia, tadalafil relaxes the muscles of the bladder and prostate, making it easier to urinate and reducing symptoms. Tadalafil should be stored at room temperature, between 68 F to 77 F (20 C to 25 C). It can be exposed to temperatures between 59 F to 86 F (15 C to 30 C) for shorter periods of time, such as cialis pills 20 mg when transporting it.