Viagra 50 mg Tablets are a prescription medication containing sildenafil citrate 50
- Always take sildenafil with a full glass of water.
- Use the medication responsibly to avoid dependency.
- Do not share your medication with others.
- Regular check-ups are recommended during use.
- Report any vision or hearing disturbances immediately.
- Use caution if combining with antihypertensive drugs.
- It is not intended for use in erectile enhancement alone.
- Follow legal and medical guidelines for purchase.
mg, widely used for the treatment of erectile dysfunction (ED) in adult men.
| Brand Name | Approximate Price per Pack | Availability | Notes |
|---|---|---|---|
| Viagra (Pfizer) | $30-$60 for 4 tablets | Widely available online and pharmacies | Brand-name, prescription required |
| Generic Sildenafil | $10-$20 for 4 tablets | Over-the-counter or prescription | Often more affordable |
| Local pharmacies | Varies | Market dependent | Check quality and authenticity |
| Online vendors | Varies | Ensure pharmacy legitimacy | Beware of counterfeit products |
Sildenafil helps enhance the natural process of erection by
- Sildenafil 50 mg is effective for most men within 30 minutes.
- Duration of effect lasts about 4-6 hours.
- It does not cause an erection without sexual stimulation.
- The medication does not protect against sexually transmitted diseases.
- Report any adverse reactions to your healthcare provider.
- Do not combine sildenafil with recreational drugs like poppers.
- Regular use may improve sexual performance over time.
- Always check for allergies before use.
increasing blood flow to the penis in response to
- Sildenafil 50 mg works best with sexual arousal.
- Do not take it with other ED medications simultaneously.
- Keep hydrated but avoid excessive alcohol intake.
- The drug is not a cure but manages symptoms.
- Some users may experience nasal congestion.
- Stay informed about possible interactions with supplements.
- Do not use expired medication.
- Follow up with your doctor for ongoing assessment.
sexual stimulation, allowing many men with ED to achieve
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The American Society of Health-System Pharmacists, Inc. makes no representations or warranties, express or implied, including, but not limited to, any implied warranty or merchantability and/or fitness for a particular purpose, with respect to such database and specifically disclaims all such warranties and representations. Users are advised that decisions regarding drug therapy are complex medical decisions requiring the independent, informed decision of an appropriate health care professional, and the database if provided for informational purposes only. The entire monograph for a drug should be reviewed for a throrough understanding of the drug's actions, uses and side effects. The American Society of Health-System Pharmacists, Inc.
Drug Interactions
does not endorse or recommend the use of any drug in the database. The information contained in the database is not a substitute for medical care or treatment by a licensed health care provider. Get 40% off on 1st online pharmacy purchase Use Code: NEW40 Primary Use: Treatment of erectile dysfunction (ED) Used in the treatment of erectile dysfunction (ED) Helps enhance penile blood flow by promoting smooth muscle relaxation and vasodilation in response to sexual stimulation Balanced 50 mg dose that often offers effective performance with a manageable side-effect profile Disclaimer: This product is a prescription-only medicine and must be used strictly under the supervision of a licensed healthcare professional. Always adhere to the directions provided on the prescription label. Consult your doctor if you have any questions or concerns regarding its use. and maintain an erection that is adequate for sexual intercourse.
| Product | Dosage | Quantity + Bonus | Price | |
|---|---|---|---|---|
| Viagra Generic | 100mg | 360 + 10 Pills | 330.21€ 314.49€ | |
| Viagra Generic | 150mg | 270 + 10 Pills | 326.61€ 311.06€ | |
| Viagra Generic | 50mg | 90 + 6 Pills | 107.37€ 102.26€ | |
| Viagra Generic | 100mg | 120 + 6 Pills | 149.50€ 142.38€ | |
| Kamagra Polo | 100mg | 32 Pills | 125.88€ 119.89€ | |
| Kamagra Soft Tabs | 100mg | 32 Pills | 120.11€ 114.39€ | |
| Kamagra Polo | 100mg | 84 + 4 Pills | 244.49€ 232.85€ | |
| Viagra Generic | 200mg | 180 + 10 Pills | 277.56€ 264.34€ | |
| Viagra Generic | 25mg | 30 + 4 Pills | 47.97€ 45.69€ | |
| Viagra Generic | 100mg | 10 Pills | 28.91€ 27.53€ | |
| Viagra Generic | 200mg | 360 + 10 Pills | 481.98€ 459.03€ | |
| Kamagra Soft Tabs | 100mg | 12 Pills | 57.55€ 54.81€ | |
| Viagra Generic | 150mg | 60 + 4 Pills | 111.25€ 105.95€ | |
| Kamagra Oral Jelly | 100mg | 90 + 8 Sachets | 303.56€ 289.10€ | |
| Viagra Generic | 50mg | 60 + 4 Pills | 83.93€ 79.93€ | |
| Kamagra Soft Tabs | 100mg | 84 + 4 Pills | 233.05€ 221.95€ |
By preserving cGMP levels, Viagra supports improved vascular
Mechanism of action
[1][26][67][91][131] Plasma concentrations of the active N-desmethyl metabolite are approximately 40% of those observed with sildenafil, and the metabolite reportedly accounts for about 20% of sildenafil's pharmacologic activity. [1][67][131] The N-demethylated metabolite, the major circulating metabolite, has a phosphodiesterase selectivity profile similar to that of sildenafil and an in vitro potency for PDE type 5 of approximately 50% of the parent drug. [1][116][131] Sildenafil is eliminated mainly in the feces as metabolites following oral administration. [1][67][91][116][131] In healthy adults and those with ED, approximately 80% of an oral dose is excreted as metabolites in feces and 13% is excreted in urine. Importance of instructing patients to read the manufacturer's patient information before starting sildenafil therapy and each time their prescription is refilled.
Patient resources
[1]Instruct patients to avoid contraindicated medications such as regular and/or intermittent use of organic nitrates, organic nitrites (e.g., ''poppers''), and riociguat. [1]Inform patients that sildenafil is marketed for erectile dysfunction (Viagra) and pulmonary arterial hypertension (Revatio®). [1] Advise patients taking Viagra® not to take Revatio® or other PDE type 5 inhibitors. [1]Advise patients of the potential for sildenafil to augment the blood pressure lowering effect of α-adrenergic blocking agents (e.g., doxazosin) and anti-hypertensive medications (e.g., amlodipine) and concomitant administration may lead to symptomatic hypotension in some patients. [1]Inform patients taking sildenafil for erectile dysfunction and with potential for cardiac risk of sexual activity (e.g., patients with preexisting cardiovascular risk factors) to refrain from further activity and seek medical attention immediately if they experience symptoms (e.g., chest pain, dizziness, nausea) upon initiation of sexual activity.
The Bottom Line
[1]Advise patients to seek immediate sildenafil 130mg medical attention for a sudden loss of vision in one or both eyes while taking sildenafil. [1] Such an event may be a sign of non-arteritic anterior ischemic optic neuropathy (NAION), a cause of decreased vision including possible permanent loss of vision. [1]Advise patients to seek prompt medical attention in the event of sudden decrease or loss of hearing while taking sildenafil. [1] These events may be accompanied by tinnitus and dizziness. [1]Advise patients to seek prompt medical attention for an erection that lasts more than 4 hours. function in the penis when sexual stimulation is present. It's important to understand that Viagra does not cause an
- Sildenafil 50 mg may cause flushing and nasal stuffiness.
- Do not use if allergic to sildenafil or similar drugs.
- Patients should discuss health history before use.
- It may take longer to work in some individuals.
- Do not use as a performance enhancer.
- Avoid using other medications without doctor approval.
- Keep a record of any side effects experienced.
- Inform your doctor if you are pregnant or breastfeeding.
erection without sexual arousal, it enhances the body's natural response.
| Attribute | Description | Notes |
|---|---|---|
| Active Ingredient | Sildenafil citrate | 50 mg per tablet |
| Mechanism of Action | PDE5 enzyme inhibition to promote vasodilation | Enhances blood flow for erectile function |
| Onset of Action | 30-60 minutes | Varies with food intake |
| Duration of Effect | Up to 4-6 hours | Effect duration can vary |
| Metabolism | Primarily processed in the liver through CYP3A4 and CYP2C9 enzymes | Potential drug interactions |
| Contraindications | Use with nitrates or contraindicated in severe cardiovascular conditions | Precautions required |
The 50 mg dose is often prescribed as a balanced option
Eroxon Erectile Dysfunction Treatment Gel - 4 Tubes
[1][4][33][34][91][127][130][131][132] Sildenafil also exhibits some activity against other PDE isoenzymes. [1][4][5][31][44][57][67][87][88] In vitro, sildenafil is about 10 times more active against PDE type 5 than against PDE type 6, greater than 70-80 times more active against PDE type 5 than against PDE type 1, greater than 1000 times more active against PDE type 5 than against PDE types 2 and 4, and 4000 times more active against PDE type 5 than against PDE type 3. [1][4][27][31][45][52][55][57][67][87][88] The duration of erectile responsiveness (i.e., the time period in which adequate sexual stimulation can produce an erection) with oral sildenafil has been reported to be approximately 2 hours, with some penile responsiveness persisting for up to 4 hours after oral administration. [1] In the largest clinical study published to date, the onset and duration of action of oral sildenafil were not reported. [33][34] In most other placebo-controlled studies in which improvement in erection was determined by penile plethysmography, the erectile effect was determined at a fixed time of 60 minutes after an oral dose of the drug.
Related treatment guides
Sildenafil is rapidly absorbed following oral administration; the mean absolute bioavailability is 41% (range, 25-63%). [1][4][56][67][91][116][249] Although studies indicate that more than 90% of an oral sildenafil dose is absorbed from the GI tract, the drug undergoes extensive metabolism in the GI mucosa during absorption and on first pass through the liver, with only about 40% of a dose reaching systemic circulation unchanged. [1][4][56][67][91][116][131][249] Pharmacokinetics of the drug (as determined by peak plasma concentrations or AUC) are dose proportional over the single-dose range of 1.25-200 mg.[1][4][56][91][116][131] Peak plasma concentrations of sildenafil and its active N-desmethyl metabolite are achieved within 30-120 (median: 60) minutes following oral administration in fasting adults. [1][4][91][127][130][249] Administration with a high-fat meal delays GI absorption, with a reduction in peak plasma concentrations of about 29% and a delay in time to peak plasma concentrations of about 60 minutes; the extent of absorption is not affected. Sildenafil appears to be widely distributed in the body.
Revatio Injection
[1][4][67][116][131] Sildenafil and its major circulating N-desmethyl metabolite are each approximately 96% bound to plasma proteins; protein binding reportedly is independent of plasma concentration. [1][67][91][116][131] Sildenafil is distributed to a limited extent in semen following oral administration, with less than 0.001% of a single dose appearing in semen 90 minutes after dosing in healthy individuals. [1][67] Such concentrations are unlikely to cause any effects in sexual partners exposed to the semen. [67] Plasma sildenafil concentrations appear to decline in a biphasic manner following oral administration, with a terminal elimination half-life of about 4 hours (range: 3-5 hours). [1][4][67][91][116][127][130][131] Sildenafil is metabolized principally via hepatic cytochrome P-450 (CYP) microsomal isoenzymes 3A4 (major route) and 2C9 (minor route). that provides effectiveness while maintaining a
| Patient Group | Recommended Dosage | Administration Timing | Special Considerations |
|---|---|---|---|
| Adult Men with ED | 50 mg as needed | 30 to 60 minutes before sexual activity | Adjust based on efficacy and tolerability |
| Elderly Patients | Same as adults, starting with lower dose | 50 mg usually appropriate | Monitor for side effects |
| Patients with Liver Impairment | Consult healthcare provider | Dose adjustments may be necessary | Increased risk of side effects |
| Patients on CYP3A4 inhibitors | Lower dose recommended | Due to increased drug levels | e.g., ketoconazole, ritonavir |
favorable tolerability profile for many patients.
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[1] If it is not treated right away, priapism can permanently damage the penis. [1]Inform patients taking sildenafil for erectile dysfunction that the drug offers no protection against sexually transmitted diseases and patients should use necessary protective measures to guard against such diseases, including the human immunodeficiency virus (HIV). [1]Instruct the patient to seek medical attention immediately if they take too much sildenafil. [1]Inform patients of the risk of symptomatic low blood pressure (e.g., dizziness, lightheadedness, fainting). [1] Monitor blood pressure when administering sildenafil in combination with blood pressure lowering drugs (e.g., α-adrenergic blocking agents).
Other Medical Problems
[1]Advise patients to take sildenafil with or without food 1 hour or, if needed, 30 minutes to 4 hours before sexual activity. [1] Inform patients that taking sildenafil with a high-fat meal may cause delayed onset. [1]Advise patient to inform their clinician of existing or contemplated concomitant therapy, including prescription and OTC drugs and dietary or herbal supplements, as well as any concomitant illnesses. [1]Inform patients of other important precautionary information. Excipients in commercially available drug preparations may sildenafil 12.5 mg have clinically important effects in some individuals; consult specific product labeling for details.
Study of Flexible Dose Escalation, Efficacy, and Safety with a Long-Term, Open-Label Extension
Please refer to the ASHP Drug Shortages Resource Center for information on shortages of one or more of these preparations. \* available from one or more manufacturer, distributor, and/or repackager by generic (nonproprietary) name © Copyright, 1959-2026, Selected Revisions April 10, 2024. American Society of Health-System Pharmacists®, 4500 East-West Highway, Suite 900, Bethesda, Maryland 20814. The American Society of Health-System Pharmacists, Inc. represents that the database provided hereunder as formulated with a reasonable standard of care, and in conformity with professional standards in the field.